This series is a searing indictment of Big Pharma and the political operatives and government regulations that enable over-production, reckless distribution and abuse of synthetic opiates. Exploring the origins, extent and fallout of one of the most devastating public health tragedies of our time, with half a million deaths from overdoses this century alone, the film reveals that America's opioid epidemic is not a public health crisis that came out of nowhere.
In the first part, a look at how Purdue Pharma worked with the FDA to get OxyContin approved for wider use, promoting the highly profitable pain medication's safety without sufficient evidence, and creating a campaign to redefine pain and how it's treated.

Dr George McGavin and Dr Zoe Laughlin set up base camp at one of the UK's biggest sewage works to investigate the revolutionary science finding vital renewable resources and undiscovered life in human waste.
Teaming up with world-class scientists, they search for biological entities in sewage with potentially lifesaving medical properties, find out how pee can generate electricity, how gas from poo can fuel a car and how nutrients in waste can help solve the soil crisis. They follow each stage of the sewage treatment process, revealing what the stuff we flush can tell us about how we live today, and the mind boggling biotechnology being harnessed to clean it, making the wastewater safe enough to return to the environment.

The film exposes the dark world of ivory trafficking. Ivory is a prized status symbol for middle class Chinese, and poachers in pursuit of elephants in Africa are causing a great damage. Award-winning director Richard Ladkani and Kief Davidson filmed undercover for 16 months infiltrating and documenting the deep-rooted corruption at the heart of the global ivory trafficking crisis.

With a million species at risk of extinction, Sir David Attenborough explores how this crisis of biodiversity has consequences for us all, threatening food and water security, undermining our ability to control our climate and even putting us at greater risk of pandemic diseases.
Everything in the natural world is connected in networks that support the whole of life on earth, and we are losing many of the benefits that nature provides to us. The loss of insects is threatening the pollination of crops, while the loss of biodiversity in the soil also threatens plants growth.
Last year, a UN report identified the key drivers of biodiversity loss, including overfishing, climate change and pollution. But the single biggest driver of biodiversity loss is the destruction of natural habitats. Seventy-five per cent of Earth's land surface (where not covered by ice) has been changed by humans, much of it for agriculture, and as consumers we may unwittingly be contributing towards the loss of species through what we buy in the supermarket. Human activities like the trade in animals and the destruction of habitats drive the emergence of diseases. Disease ecologists believe that if we continue on this pathway, this year’s pandemic will not be a one-off event.

Did China hide crucial information about Covid-19 from the world? What began with a handful of mystery pneumonia cases in Wuhan late last year has now left more than half a million dead worldwide. Beijing says it has been open and transparent throughout, but former BBC China Editor Carrie Gracie investigates how it delayed reporting the initial outbreak and evidence that Covid-19 could be spread by people. It also silenced doctors who tried to speak out.
The film also hears from one high-level insider who believes the animal market at the centre of the Wuhan outbreak should have been treated as a 'crime scene' and from experts who warn that this crisis may be a 'dress rehearsal' for an even more deadly pandemic in the future.

In just over 100 days, a new coronavirus has taken an unprepared world by storm, infiltrating every corner of the globe, sending entire nations into lockdown, killing thousands and infecting countless more. Across the world, governments are scrambling to react, hospitals are struggling to cope and an increasingly anxious public are starting to panic.
The world's media is awash with data, information and misinformation. But what are the facts? What is COVID-19 and why is this strain of coronavirus so dangerous? What happens in our bodies when the virus attacks? How does this compare to previous pandemics? What do all the the numbers really mean, and how can data modelling help us look for an exit strategy? This programme investigates the scientific facts and figures behind the biggest public health crisis in living memory, and explores the latest research from the frontline of the medical and scientific fightback.