How do the five senses really work? In fact, there are many more than five, and they all work together to create our own version of reality. We dive into the stories of a pairs figure skating team, a perfumer, a cave explorer, and a musician to decipher how different ways of sensing the world all create their own vivid, and unique, picture.
This episode explores the world of human sensation and how it defines reality.

The cosmos, with its billions of galaxies and countless stars, isn't the only one. We share our lives with another universe: The world of the small, of the viruses, of the bacteria. We call this strange hidden kingdom the Microcosmos. We share our world with the microcosmos. Will we coexist in an uneasy peace, or will it destroy us?
In 2020, A tiny virus caused a global pandemic, COVID-19. This pandemic makes people see the world completely differently, because there was an invisible universe, pretty much ignored for the most part. Very, very tiny things have a huge impact on our lives. The microcosmos is complex, while some parts kill us, others keep us alive. The microcosmos is responsible for the very oxygen that we breathe and the soil on which we live. And it will influence our future as we venture out into space.

In this mind-bending series, Professor Jim Al-Khalili explores the vast range of size in the universe, from tiny atoms to gigantic, interconnected galaxies.
In the first episode, Jim will enter the world of objects that are too tiny to glimpse with the naked eye. Starting with the smallest insects, he moves on to encounter living cells with amazing superpowers and confronts some of humanity's deadliest enemies in the form of viruses. Going smaller still, he encounters wondrous new nanomaterials such as graphene, discovered by physicist Andre Geim. These are revolutionising engineering, medicine, computing, electronics and environmental science. Finally, Jim comes face to face with the fundamental building blocks of the world around us – atoms – and reveals why understanding the science of the 'small' is crucial to the future of humanity.

The last episode explores Mescaline, the psychoactive molecule in San Pedro and peyote cacti, a sacred medicine that Native Americans have had to fight for the right to use. At the Indigenous practices there's always an elder, someone who knows the territory very well, who's presiding. There's usually a group, a community is involved, There's always an intention, a purpose to what you're doing, and you're treating it as sacred, in order to achieve altered states of consciousness, which contribute to worship in various ways, or celebration or healing.
But maybe all this is not so new to Western culture after all. In the old Greek histories of Eleusis, people who were initiated there got the drink, the kykeon, and then they had the illumination. The precise recipe is a mystery, but we know that the kykeon was a psychoactive brew that was used at the Eleusinian mysteries, a sacred annual ritual of enlightenment practiced by some of the world's greatest minds including Socrates, Plato, and Aristotle. So why did this ritual come to an end more than 1,000 years ago? Was the possibility of illumination or achieving a higher consciousness considered threatening to the powers that be? Have the drug wars been merely an extension of that fear?
Psychedelics has a major part in how we can heal as a community, how we can heal as a city, and how we can heal as a country. The current renaissance of psychedelics could not come at a better time as the world confronts a crisis in mental health. But psychedelics have much to offer. The psychedelic experience changes the mind in ways that will help scientists better understand how it works. All these altered states allow us to probe what is the greatest mystery in all of nature. The emergence from mere matter of something as miraculous as consciousness. But an even bigger question is whether psychedelics might help us address the environmental crisis of how we think about our place in nature. One of the greatest gifts of psychedelics is how they reanimate the natural world, allowing us to perceive the subject, the spirit of all species, not just our own. And to feel a deeper sense of interconnectedness with nature.

Magic mushrooms, long considered sacred by the Indigenous Mazatec in Mexico, become the subject of scientific studies measuring the intense effects of its Psilocybin and its potential therapeutic use.
In the second episode, we are introduced to Ben, who’s battled with crippling Obsessive-Compulsive Disorder (OCD) his entire life. When he had his firstborn, Ben’s life became full of panic attacks regarding his son’s safety, and he knew something had to change. Ben signed up for a psilocybin-assisted therapy clinical trial which was testing whether the psychedelic could help people with severe OCD. In the session under the influence of psilocybin, Ben felt decomposed and eventually grew into a tree. While living as a tree, he saw his human self, playing with his child. Though this sounds scary, from Ben’s perspective, it was beautiful. He was one with the universe, seeing himself in the ultimate third-person perspective. Finally, he saw how it could be different if he didn’t let his OCD control him. And several months out, all the symptoms disappeared.
Ben’s story is one of many told in this series, which gives hope that help is right around the corner for the millions who suffer —often in silence— with debilitating mental disorders. But Michael Pollan’s work is showcasing the success stories. Often, even in the most successful trials, psychedelic-assisted therapy only helps up to a third of people enter remission. More frequently, patients are helped —sometimes substantially— but they still suffer with their illnesses and some people aren’t helped at all.

Championed by both therapists and ravers, ecstasy stands out as the first psychedelic likely to become legalized, thanks to passionate advocates.
The episode about 3,4-Methylenedioxymethamphetamine (MDMA), is focused on Multidisciplinary Association for Psychedelic Studies (MAPS) clinical trials treating Post-traumatic stress disorder (PTSD).