Horizon investigates the idea that the best way to lose weight successfully is a personalised approach, diets tailored to our individual biology and psychology. In a groundbreaking experiment, Dr Chris van Tulleken and Tanya Byron join a team of experts to put 75 overweight volunteers on diets designed to tackle the specific reasons why they eat too much. The volunteers are put through a series of tests at a residential clinic to understand how their genes, hormones and psychology influence their eating behaviour. They are then put on the diets the experts believe are best suited to them. Can science succeed where other diets have failed?

Explore the latest science behind the headlines and the coolest scientific developments that impact our lives. Technology catapults to new heights in 2015, going faster and further than ever before. We have canvassed the world in search of the best and most fascinating science and tech stories of the year for 2015 YEAR IN SCI-TECH". This action-packed hour of fun and intrigue revisits the world’s first glimpse of Pluto and images of water on Mars while exploring what this all could mean for intelligent life in the universe – all while earthling’s inch closer to becoming actual space tourists. Throughout the hour, we revisit the year’s most amazing techological feats and scientific discoveries, including new and elusive animal species discovered deep under the ocean, as well as the hottest tech trends – from hover boards to driverless cars and trucks, and the newest advances in mind-blowing virtual reality.

Adam Rutherford meets a new creature created by American scientists, the spider-goat. It is part goat, part spider, and its milk can be used to create artificial spider's web. It is part of a new field of research, synthetic biology, with a radical aim: to break down nature into spare parts so that we can rebuild it however we please. This technology is already being used to make bio-diesel to power cars. Other researchers are looking at how we might, one day, control human emotions by sending 'biological machines' into our brains.

The extraordinary wildlife, culture and history of this immense, fascinating ocean and its myriad islands are revealed in stunning detail. With its coral reefs, turquoise lagoons and dramatic oceanic atolls, the South Pacific is the archetypal paradise. It is still relatively healthy and teeming with fish, but it is a fragile paradise. International fishing fleets are taking a serious toll on the sharks, albatross and tuna, and there are other insidious threats to these bountiful seas. We look at what is being done to preserve the ocean and its wildlife.

Professor of physics Jim Al-Khalili investigates the most accurate and yet perplexing scientific theory ever - quantum physics, the perplexing theory of sub-atomic particles. Turning his attention to the world of nature, can quantum mechanics explain the greatest mysteries in biology? The European robin navigates using one of the most bizarre effects in physics - quantum entanglement, a process which seems to defy common sense. Jim finds that even the most personal of human experiences - our sense of smell - is touched by ethereal quantum vibrations. According to new experiments it seems that our quantum noses are listening to smells. Jim discovers that the most famous law of quantum physics - the uncertainty principle - is obeyed by plants and trees as they capture sunlight during the vital process of photosynthesis. Jim wonders if the strange laws of the sub-atomic world, which allow objects to tunnel through impassable barriers in defiance of common sense, could effect the mechanism by which living species evolve?

What triggered the incredible diversity of life on Earth, and how have complex life forms, including humans, evolved? Is there direction to evolution? And is human intelligence inevitable? This program focuses on evolution's 'great transformations' —among them the development of a standard four-limbed body plan, the journey from water to land, the return of marine mammals to the sea, and the emergence of humans. Driven by a combination of opportunism and a genetic 'toolkit', these astounding leaps forward define the arc of evolution. And they suggest that every living creature on earth today, and every species that has ever existed, is a variation on a grand genetic theme—a member of one, and only one, tree of life