Horizon investigates the idea that the best way to lose weight successfully is a personalised approach, diets tailored to our individual biology and psychology. In a groundbreaking experiment, Dr Chris van Tulleken and Tanya Byron join a team of experts to put 75 overweight volunteers on diets designed to tackle the specific reasons why they eat too much. The volunteers are put through a series of tests at a residential clinic to understand how their genes, hormones and psychology influence their eating behaviour. They are then put on the diets the experts believe are best suited to them. Can science succeed where other diets have failed?

Dr Michael Mosley and Professor Alice Roberts investigate if male and female brains really are wired differently. New research suggests that the connections in men and women's brains follow different patterns, patterns which may explain typical forms of male and female behaviour. But are these patterns innate, or are they shaped by the world around us?" Using a team of human lab rats and a troop of barbary monkeys, Michael and Alice test the science and challenge old stereotypes. They ask whether this new scientific research will benefit both men and women - or whether it could drive the sexes even further apart.

Dr Michael Mosley traces the sinister ways the experimental psychology has used to try to control our minds. He finds that the pursuit of mind control has led to some truly horrific experiments and left many casualties in its wake. Extraordinary archive captures what happened - scientists systematically change the behaviour of children; law abiding citizens give fatal electric shocks; a gay man has electrodes implanted in his head in an attempt to turn his sexuality. Michael takes a hallucinogenic drug as part of a controlled experiment to try to understand how its mind-bending properties can change the brain. This is a scientific journey goes to the very heart of what we hold most dear - our free will, and our ability to control our own destiny.

Roses are red, violets are blue but according to the latest understanding these colours are really an illusion. One that you create yourself. Horizon reveals a surprising truth about how we all see the world. You may think a rose is red, the sky is blue and the grass is green, but it now seems that the colours you see may not always be the same as the colours I see. Your age, sex and even mood can affect how you experience colours. Scientists have unlocked the hidden power that colours can have over your life - how red can make you a winner, how blue makes time speed up. Watch an experiment where for people in a blue pod, a minute lasts 11 seconds shorter.

We all agree lying is shameful. Yet we still deliberately deceive each other constantly. Are our brains wired for lying from a young age? The brains of pathological liars may provide insights. Will technology make it easier for us to be dishonest, or could it someday instantly reveal someone is lying? Perhaps we are deceitful because our limited senses prevent us from seeing the real truth. Scientists say our own memories deceive us, and have managed to implant false memories. Other scientists look for ultimate truth in the subatomic world … only to end up turning reality on its head.

We now know that the brain - the organ that more than any other makes us human - is one of the wonders of the universe, and yet until the 17th century it was barely studied. The twin sciences of brain anatomy and psychology have offered different visions of who we are. Now these sciences are coming together and in the process have revealed some surprising and uncomfortable truths about what really shapes our thoughts, feelings and desires. And the search to understand how our brains work has also revealed that we are all - whether we realise it or not - carrying out science from the moment we are born.