Tony Accardo have taken the reins of the criminal empire built by their mentor Al Capone. Thanks to Sam Giancana's takeover of the policy racket, the gangsters are now making millions. With so much money coming in, Accardo knows they need a place to hide it. They find their answer in a growing city where gambling is now legal: Las Vegas. However, the New York mafia is already there, led by criminal mastermind Meyer Lansky.

Michael Wood’s epic series moves on to the revolutionary years after 500BC - the Age of the Buddha. Travelling by rail to the ancient cities of the Ganges plain, by army convoy through Northern Iraq, and on down the Khyber Pass, he shows how Alexander the Great’s invasion of India inspired her first empire.

Some of the world's leading physicists believe they have found startling new evidence showing the existence of universes other than our own. One possibility is that the universe is so vast that an exact replica of our solar system, our planet and ourselves exists many times over. These Doppelganger Universes exist within our own Universe; in what scientist now call "The Multiverse." If proof is found it will change our lives, our minds, our planet, our science and our universe.

This episodes the nature of the cosmos on the micro and atomic scales, using the Ship of the Imagination to explore these realms. Tyson describes some of the micro-organism that live within a dew drop, demonstrating parameciums and tardigrades. He proceeds to discuss how plants use photosynthesis via their chloroplasts to convert sunlight into chemical reactions that convert carbon dioxide and water into oxygen and energy-rich sugars. Tyson then discusses the nature of molecules and atoms and how they relate to the evolution of species. He uses the example set forth by Charles Darwin postulating the existence of the long-tongued Morgan's sphinx moth based on the nature of the comet orchid with pollen far within the flower. He further demonstrates that scents from flowers are used to trigger olfactory centers in the brain, stimulating the mind to threats as to aid in the survival of the species. Tyson narrates how Greek philosophers Thales and Democritus postulated that all matter was made up of combinations of atoms in a large number of configurations, and describes how carbon forms the basic building block for life on earth due to its unique chemical nature. Tyson explains on the basic atomic structure of protons, neutrons, and electrons, and the nature of nuclear fusion that occurs in most stars. He then discusses the existence of neutrinos that are created by these nuclear processes in stars, and that detecting such sub-atomic particles which normally pass through matter require subterranean facilities like the Super-Kamiokande that were used to detect neutrinos from the supernova SN 1987A in the Large Magellanic Cloud before light from the explosion were observed due to their ability to pass through matter of the dying sun. Tyson compares how neutrinos were postulated by Wolfgang Pauli to account for the conservation of energy from nuclear reactions in the same manner as Darwin's postulate on the long-tongued moth. Tyson concludes by noting that there are neutrinos from the Big Bang still existing in the universe but due to the nature of light, there is a "wall of infinity" that cannot be observed beyond.

In the high-stakes game of big-wall climbing, the Shark’s Fin on Mount Meru may be the ultimate prize. Sitting at the headwaters of the sacred Ganges River in Northern India, the Shark’s Fin has seen more failed attempts by elite climbing teams over the past 30 years than any other ascent in the Himalayas. To undertake Meru, says Jon Krakauer, the bestselling author of Into Thin Air, "You can’t just be a good ice climber. You can’t just be good at altitude. You can’t just be a good rock climber. It’s defeated so many good climbers and maybe will defeat everybody for all time. Meru isn’t Everest. On Everest you can hire Sherpas to take most of the risks. This is a whole different kind of climbing."

In less than two years, Al Capone has risen from a humble bookkeeper to second-in-command of Johnny Torrio's criminal empire in Chicago. The empire is worth the modern-day equivalent of $35 million. Capone purchases a home for his family and moves them from New York to Chicago. Torrio and Capone expand their empire from Chicago's South Side to the North Side, which is controlled by Chicago's second largest gang, the Irish. Violence erupts as ruthless Irish gang leader Dean O'Banion protects his territory and bootlegging business from Torrio and Capone.