In AD 410, the Goth hordes sacked the city. This event symbolised Rome's collapse. Within 70 years, the western empire - what we think of as Ancient Rome - was abandoned. But it should never have happened at all.

The story of how the secret of life has been examined through the prism of the most complex organism known - the human body. It begins with attempts to save the lives of gladiators in Ancient Rome, unfolds with the macabre work and near-perfect drawings of Leonardo in the Renaissance, through the idea of the 'life force' of electricity, to the microscopic world of the cell. It reveals how a moral crisis unleashed by work on the nuclear bomb helped trigger a great breakthrough in biology - understanding the structure and workings of DNA.

Rome was once a largely democratic society, with regular elections. This Republic lasted for 500 years, but then came Tiberius Gracchus. He believed in the ideals of the Republic - fairness, decency and justice for everyone -but was appalled by Rome's aristocrats' treatment of the poor. So he unleashed the power of the mob upon the streets of Rome, with devastating consequences.

Writing itself is 5,000 years old, and for most of that time words were written by hand using a variety of tools. The Romans were able to run an empire thanks to documents written on papyrus. Scroll books could be made quite cheaply and, as a result, ancient Rome had a thriving written culture. With the fall of the Roman Empire, papyrus became more difficult to obtain. Europeans were forced to turn to a much more expensive surface on which to write: Parchment. Medieval handwritten books could cost as much as a house, they also represent a limitation on literacy and scholarship.
No such limitations were felt in China, where paper had been invented in the second century. Paper was the foundation of Chinese culture and power, and for centuries how to make it was kept secret. When the secret was out, paper mills soon sprang up across central Asia. The result was an intellectual flourishing known as the Islamic Golden Age. Muslim scholars made discoveries in biology, geology, astronomy and mathematics. By contrast, Europe was an intellectual backwater.
That changed with Gutenberg’s development of movable type printing. The letters of the Latin alphabet have very simple block-like shapes, which made it relatively simple to turn them into type pieces. When printers tried to use movable type to print Arabic texts, they found themselves hampered by the cursive nature of Arabic writing. The success of movable type printing in Europe led to a thousand-fold increase in the availability of information, which produced an explosion of ideas that led directly to the European Scientific Revolution and the Industrial Revolution that followed.