In this series, David Pogue explores the fantastic chemistry behind the everyday and sets out on a worldwide quest to find the key molecules and chemical reactions that have paved the way for human civilization, life, and even the universe as we know it.
In the first episode, glass so strong you can jump on it, rubber so tough it protects a clay pot dropped from 50 feet, endless varieties of plastic. Scientists and engineers have created virtually indestructible versions of common materials by manipulating the chains of interlocking atoms that give them strength—but have they made them too tough?

Without the chemistry of photosynthesis, ozone, and a molecule called Rubisco, none of us would be here. So how did we get so lucky? To find out, host David Pogue investigates the surprising molecules that allowed life on Earth to begin, and ultimately thrive. Along the way, he finds out what we’re all made of—literally.

Just about every solid, liquid, or gas in the world as we know it begins with reactions between individual atoms and molecules. Host David Pogue dives into the transformative world of chemical reactions, from the complex formula that produces cement to the single reaction that’s allowed farmers to feed a global population by the billions.

Physicist Jim Al-Khalili travels through Syria, Iran, Tunisia and Spain to tell the story of the great leap in scientific knowledge that took place in the Islamic world between the 8th and 14th centuries. Its legacy is tangible, with terms like algebra, algorithm and alkali all being Arabic in origin and at the very heart of modern science - there would be no modern mathematics or physics without algebra, no computers without algorithms and no chemistry without alkalis. For Baghdad-born Al-Khalili, this is also a personal journey, and on his travels he uncovers a diverse and outward-looking culture, fascinated by learning and obsessed with science. From the great mathematician Al-Khwarizmi, who did much to establish the mathematical tradition we now know as algebra, to Ibn Sina, a pioneer of early medicine whose Canon of Medicine was still in use as recently as the 19th century, Al-Khalili pieces together a remarkable story of the often-overlooked achievements of the early medieval Islamic scientists.

Al-Khalili travels to northern Syria to discover how, a thousand years ago, the great astronomer and mathematician Al-Biruni estimated the size of the earth to within a few hundred miles of the correct figure. He discovers how medieval Islamic scholars helped turn the magical and occult practice of alchemy into modern chemistry. In Cairo, he tells the story of the extraordinary physicist Ibn al-Haytham, who helped establish the modern science of optics and proved one of the most fundamental principles in physics - that light travels in straight lines. Prof Al-Khalili argues that these scholars are among the first people to insist that all scientific theories are backed up by careful experimental observation, bringing a rigour to science that didn't really exist before.

In the dark depths of the oceans, nearly 90% of all species light up the darkness from within. These creatures flash, sparkle, shimmer, or simply glow. Whether it’s to scare off predators, fish for prey, or lure a mate, the language of light is everywhere in the ocean depths, and scientists are finally starting to decode it. Discover surprising ways to harness nature’s light—from tracking cancer cells to detecting pollution, lighting up cities, and even illuminating the inner workings of our brains.