This episode discusses the human exploration of Antarctica, in particular the mission led by Captain Robert Falcon Scott, whose team died on the way back from the South Pole. It shows the scientific work in the modern human bases in Antarctica, especially Mawson Base and its observation of Adelie Penguins (partially through tracking devices). The second half of the episode describes how the series was made. Most crucial was of course the camera work. To get access to the wildlife of the sea, for example, boats, divers, suspended capsules and remotely controlled cameras mounted on inflatables were used. Particularly dangerous to divers were Leopard Seals and other predators. The film concludes that although working in Antarctica is now much easier than during the early days of exploration, human footsteps on the continent are still exceedingly rare in part because of international treaties prohibiting industrial exploitation.

Sagan discusses the story of the Heike crab and artificial selection of crabs resembling samurai warriors, as an opening into a larger discussion of evolution through natural selection (and the pitfalls of intelligent design). Among the topics are the development of life on the Cosmic Calendar and the Cambrian explosion; the function of DNA in growth; genetic replication, repairs, and mutation; the common biochemistry of terrestrial organisms; the creation of the molecules of life in the Miller-Urey experiment; and speculation on alien life (such as life in Jupiter's clouds). In the Cosmos Update ten years later, Sagan remarks on RNA also controlling chemical reactions and reproducing itself and the different roles of comets (potentially carrying organic molecules or causing the Cretaceous–Paleogene extinction event).

Sagan reflects on the future of humanity and the question of 'who speaks for Earth?' when meeting extraterrestrials. He discusses the very different meetings of the Tlingit people and explorer Jean-François de La Perouse with the destruction of the Aztecs by Spanish conquistadors, the looming threat of nuclear warfare, and the threats shown by destruction of the Library of Alexandria and the murder of Hypatia. The episode ends with an overview of the beginning of the universe, the evolution of life, and the accomplishments of humanity and makes a plea to mankind to cherish life and continue its journey in the cosmos. The Cosmos Update notes the preliminary reconnaissance of planets with spacecraft, the fall of the Berlin Wall and the end of apartheid in South Africa, and measures towards the reduction of nuclear weapons.

This remarkable series profiles on the major defendants of the Nuremberg war crimes trials. In the first episode, Nathaniel Parker plays the most inscrutable Nazi on trial at Nuremberg, Hitler's architect and armaments minister Albert Speer.
He was the only defendant who unreservedly accepted responsibility for the Nazis' crimes. But was Speer's remorse genuine or just a clever defense strategy to get off the hook? The film tells the intriguing behind-the scenes-story of Speer's trial and his showdown with unrepentant rival, Hermann Goering.

The second episode tells the story of the trial of Hermann Goering, Hitler's charismatic and ruthless second-in-command. On trial for his life at Nuremberg, the unrepentant Reich Marshal turned the tables on the Allies. So much so that Chief Prosecutor Justice Robert Jackson began to wish the Allies had followed Churchill's suggestion and shot the leading Nazis out of hand. This documentary drama traces the behind-the-scenes story of Goering's attempt to re-ignite Nazism from the courtroom.

Episode three explores the mind of one of the most fanatical of all Nazis and the insight that gives into the psychology of dictatorship. Hess is brought to Nuremberg from the UK where he had flown 4 years earlier much to the bemusement of the British. Overy explains that they must have quickly realised he was not normal. In the intervening time Hess’s mental state has further deteriorated and when interviewed by Chief Interrogator Colonel John Amen proclaims amnesia. Chief Interpreter Richard Sonnenfeldt explains that they brought in Göring to confront Hess but that he too failed to make an impression.
Psychopathologist Prof. Edgar Jones proposes Hess’s behaviour patterns may be his way of escaping reality as he is forced to face the extent of the atrocities and choose between accepting his part of the blame or forsaking his Führer. However, as history Professor Robert Gellatel explains it is difficult to construct a case against Hess as he was imprisoned in England when the worst of the atrocities were carried out so British Prosecutor Mervyn Griffith-Jones must argue a conspiracy charge linking the pre-1939 persecutions to the post-1939 atrocities and a crimes against peace charge proving the flight to Scotland was merely a ruse.