A ground-breaking new trial at Imperial College London sees, for the first time ever under controlled conditions, a psychedelic drug tested head-to-head against a standard antidepressant as a treatment for depression. The film follows a pioneering team of scientists and psychotherapists as they compare the effects of psilocybin (the active ingredient of magic mushrooms) with an antidepressant on a small group of participants with clinical depression. This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.
This series is a searing indictment of Big Pharma and the political operatives and government regulations that enable over-production, reckless distribution and abuse of synthetic opiates. Exploring the origins, extent and fallout of one of the most devastating public health tragedies of our time, with half a million deaths from overdoses this century alone, the film reveals that America's opioid epidemic is not a public health crisis that came out of nowhere. In the first part, a look at how Purdue Pharma worked with the FDA to get OxyContin approved for wider use, promoting the highly profitable pain medication's safety without sufficient evidence, and creating a campaign to redefine pain and how it's treated.
A Six-part Saga on the South Florida traffickers indicted in one of the largest drug cases in U.S. history. Alleged to be the chief U.S. distributors for two of Colombia's biggest cartels, Cuban exiles Augusto 'Willy' Falcon and Salvador 'Sal' Magluta were accused of smuggling over 75 tons of cocaine into the U.S. in the 1980s. The high school friends built a reputed $2 billion empire that made Willy and Sal two of Miami's biggest celebrities. Featuring colourful interviews with those closest to them, their defence team, and the Feds tasked with taking them down, the series paints a vivid portrait of the last of Miami's 'cocaine cowboys.' The first episode shows how in the 1970s and '80s, friends Willy Falcon and Sal Magluta leave humble beginnings behind as they allegedly ascend to the top of Miami's drug trade.
The war on drugs was upon them, and despite believing that they were untouchable, the authorities close in. The 'Cowboys' are left with three options: flee, flip or face the music. Falcon and Magluta, along with their associates, were ultimately arrested and tried for their crimes. But they won't go down so easily.
A huge social experiment is underway. Fifty-five million Americans say they currently use cannabis, and that number is expected to grow as voters push for legalization in more and more states. The film investigates the story of cannabis from the criminalization that has disproportionately harmed communities of color to the latest medical understanding of the plant. What risks does cannabis pose to the developing brain? How much do we know about its potential medical benefits? As cannabis becomes socially accepted, scientists are exploring its long-term health consequences.
This is scientific research at its most cutting edge. With over seven million people being prescribed antidepressants each year in England alone, this drug trial is an important milestone in understanding a completely different treatment for depression. How do psychedelic drugs measure up against the industry-standard antidepressants that have been popular since the 1990s? The empirical results of the trial are explored alongside the participants’ powerful lived experience.