We are in the grip of an allergy epidemic. 50 years ago one in 30 were affected, but in Britain today it is closer to one in three. Why this should be is one of modern medicine's greatest puzzles. In search of answers, Horizon travels round the globe, from the remotest inhabited island to the polluted centres of California and the UK. We meet sufferers and the scientists who have dedicated their lives trying to answer the mystery of why we are becoming allergic to our world.

Does life exist on other planets? Astrobiology is a visionary new science that searches for life in space by combining the disciplines of astronomy, biology and geology. How did life evolve on Earth? What will life look like on other planets? These and other pertinent questions will be answered by a diverse group of scientists. Viewers will visit the Pilbara region of West Australia where the oldest evidence of life on Earth has been discovered. Travel to the moons of Jupiter and Saturn to test a theory that life could exist in the clouds of Venus. Finally, watch as experiments are done to see if life exists on exoplanets, earth-like planets beyond our solar system.

In space travel there is a saying that the first 50 miles and the last 50 miles are the most dangerous. Explore the controlled explosion of launch, the fiery crucible of re-entry and everything in between. See how a single spark inside a spacecraft or a micrometeoroid less than an inch wide hitting a space station can turn a routine mission into a lethal nightmare. As the missions become longer, venturing to Mars and beyond, the potential disasters will only become bigger. What would happen if a spacecraft ventured too close to a black hole or was hit by a gamma ray burst?

East Africa is a land which is constantly changing. To survive here, creatures must be able to deal with unpredictable twists and turns - wet turning to dry, feast to famine, cold to hot - no matter how hostile it becomes. From dense forests to snow capped peaks, steamy swamps and endless savannah, this unique and varied land is also a haven for life, supporting large animals in numbers found nowhere else on Earth. But away from the familiar, forever-travelling herds, there are a huge cast of other characters - lizards that steal flies from the faces of lions, vast dinosaur-like birds who stalk catfish through huge wetlands, and an eagle who risks everything on the arrival of ten million bats from a far off rainforest.

'Dinosaurs: Giants of Patagonia' Following Pr Rodolfo Coria, a world-reknown Argentinian paleontologist, we visit sites of major discoveries he has contributed to in Patagonia and travel back in time to see these amazing beasts come to life in 3D. Patagonia has given us the largest living animal to ever walk the Earth: the titanesque plant-eating Argentinosaur, and its nemesis, the Giganotosaur, a bipedal carnivore that could easily challenge the famous T-Rex.

Following the Yangtze along Tiger Leaping Gorge into Yunnan in China, Palin reaches the easternmost end of the Himalayas. He gets a medical check-up before exploring medieval Lijiang with the director of the local orchestra. Heading over Myanmar to Nagaland in India he rides the steam train to Tipong Coalmine. In Assam he rides an elephant and then stays in a strange monastery.