We all agree lying is shameful. Yet we still deliberately deceive each other constantly. Are our brains wired for lying from a young age? The brains of pathological liars may provide insights. Will technology make it easier for us to be dishonest, or could it someday instantly reveal someone is lying? Perhaps we are deceitful because our limited senses prevent us from seeing the real truth. Scientists say our own memories deceive us, and have managed to implant false memories. Other scientists look for ultimate truth in the subatomic world … only to end up turning reality on its head.

There could be an undiscovered species on Earth unlike anything we’ve ever known. Not in the ocean, but the ocean itself! Its body spans thousands of miles; its heart beats with a one-thousand-year pulse. It could even have an immune system capable of annihilating all other life on earth. Just as our bodies function through the interaction of water with individual cells, including bacteria and other microorganisms, the ocean’s residents might collectively form a super-organism. A recent discovery suggests the ocean is a living being capable of thought. If so, what is the ocean thinking about us?

Aliens almost certainly do exist. So why haven't we yet met E.T.? It turns out we're only just developing instruments powerful enough to scan for them, and science sophisticated enough to know where to look. As a result, race is on to find the first intelligent aliens. But what would they look like, and how would they interact with us if we met? The answers may come to us sooner than we imagine, for one leading astronomer believes she may already have heard a hint of their first efforts to communicate

Thirty years ago, scientists first realized that some unknown dark substance was affecting the way galaxies moved. Today, they think there must be five times as much dark matter as regular matter out there. But they have no idea what it is - onl that it's not made of atoms, or any other matter we are familiar with. And Dark Matter is not the only strange substance in the Universe - a newly discovered force, called Dark Energy, seems to be pushing the very fabric of the cosmos apart.

Our universe seems real. But what if it’s a videogame? Scientists in a variety of fields are taking seriously the possibility that we live in a virtual reality. Maybe the Big Bang was just the moment someone flipped the switch and turned on our universe. Maybe what looks random has already been programmed to happen. If some advanced civilization did design and program our universe, would we ever know? Scientists are looking for glitches in the laws of the universe that may uncover its hidden code.

Are the wealthy just born in the right place at the right time? Are the poor victims of a system designed to keep them down? Or do physics and biology determine who is rich and who is poor? Throughout history, distribution of wealth is governed by hidden forces: DNA, environmental stress, patterns of human migration and even the laws of thermodynamics! Nature seems to demand winners and losers in life. But does this mean greed is king, and the rich can take what they want? Or is cooperation – between microorganisms, monkeys, and humans – more essential to survival of a species?