Do you make your own luck, or does luck make you? Some scientists believe luck is strictly a matter of statistics and probabilities…but others believe unseen forces are at work, and randomness is built into every particle of the universe. We’ll find luck, good and bad, in casinos, basketball courts, genetics labs and the subatomic world. How much does the genetic lottery rule your fate? Are lucky streaks and unfortunate accidents merely our own minds fooling us? It’s a scientific journey that will radically revise your understanding of the laws of nature and the workings of the human brain.

Particle physicist Prof. Brian Cox asks, 'What time is it?' It's a simple question and it sounds like it has a simple answer. But do we really know what it is that we're asking? Brian visits the ancient Mayan pyramids in Mexico where the Maya built temples to time. He finds out that a day is never 24 hours and meets Earth's very own Director of Time. He journeys to the beginning of time, and goes beyond within the realms of string theory, and explores the very limit of time. He discovers that we not only travel through time at the speed of light, but the experience we feel as the passing of time could be an illusion.

When man finally broke free of the Earth's gravitational pull the dream of travelling to other planets became a reality. Today scientists are proposing a bizarre array of technologies in the hope of travelling faster through space: from space craft sporting sails that catch laser beams, to propulsion engines powered by a bizarre entity known as anti-matter. Finally explore the science behind the seemingly fanciful notion of warp-drive and a theoretical particle that can travel faster than light.

Scientists have no idea what it is, but Dark Matter and Dark Energy make up 96% of the Universe. Dark Matter is everywhere. It passes through everything we know on earth at billions of particles every second, yet no one has ever gotten a direct detection of this mysterious dark substance. An even more bewildering force is Dark Energy, which is rapidly pushing apart our Universe. Discovered only ten years ago, scientists are struggling to comprehend its unusual characteristics and answer the ultimate question; what is the fate of our Universe? Using cutting-edge computer graphics watch as the universe is brought down to earth.

The simple act of making an apple pie is extrapolated into the atoms and subatomic particles (electrons, protons, and neutrons) necessary. Many of the ingredients necessary are formed of chemical elements formed in the life and deaths of stars (such as our own Sun), resulting in massive red giants and supernovae or collapsing into white dwarfs, neutron stars, pulsars, and even black holes. These produce all sorts of phenomena, such as radioactivity, cosmic rays, and even the curving of spacetime by gravity. Cosmos Update mentions the supernova SN 1987A and neutrino astronomy.

This episodes the nature of the cosmos on the micro and atomic scales, using the Ship of the Imagination to explore these realms. Tyson describes some of the micro-organism that live within a dew drop, demonstrating parameciums and tardigrades. He proceeds to discuss how plants use photosynthesis via their chloroplasts to convert sunlight into chemical reactions that convert carbon dioxide and water into oxygen and energy-rich sugars. Tyson then discusses the nature of molecules and atoms and how they relate to the evolution of species. He uses the example set forth by Charles Darwin postulating the existence of the long-tongued Morgan's sphinx moth based on the nature of the comet orchid with pollen far within the flower. He further demonstrates that scents from flowers are used to trigger olfactory centers in the brain, stimulating the mind to threats as to aid in the survival of the species. Tyson narrates how Greek philosophers Thales and Democritus postulated that all matter was made up of combinations of atoms in a large number of configurations, and describes how carbon forms the basic building block for life on earth due to its unique chemical nature. Tyson explains on the basic atomic structure of protons, neutrons, and electrons, and the nature of nuclear fusion that occurs in most stars. He then discusses the existence of neutrinos that are created by these nuclear processes in stars, and that detecting such sub-atomic particles which normally pass through matter require subterranean facilities like the Super-Kamiokande that were used to detect neutrinos from the supernova SN 1987A in the Large Magellanic Cloud before light from the explosion were observed due to their ability to pass through matter of the dying sun. Tyson compares how neutrinos were postulated by Wolfgang Pauli to account for the conservation of energy from nuclear reactions in the same manner as Darwin's postulate on the long-tongued moth. Tyson concludes by noting that there are neutrinos from the Big Bang still existing in the universe but due to the nature of light, there is a "wall of infinity" that cannot be observed beyond.