Follow the four civilians as they launch into space on a three-day trip orbiting Earth and reaching an altitude higher than that of the International Space Station. The SpaceX Dragon mission, dubbed Inspiration4, is making history as the first all-civilian mission to orbit.
In the first episode, preparations begin for the mission. The commander is Jared Isaacman, a billionaire entrepreneur who purchased the flight for all four passengers, and the second crew member is a 29-year-old cancer survivor, Hayley Arceneaux.

A fighter jet ride prepares the crew for the G-forces of spaceflight. Haley, Sian and Chris relate the emotions they experience as launch approaches.

Principles of generosity and prosperity inform the selection of the last two crew members: Christopher Sembroski, a former member of the U.S. Air Force who served in Iraq and now works as a Lockheed Martin engineer, and Sian Proctor, a professor of geosciences and two-time NASA astronaut candidate. Excitement for the flight ramps up, but anxiety lingers.

As training begins, the crew members process the physical, mental and technical demands being placed on them. The group is going to be in some intentionally uncomfortable situations and, to see how they do as a team. A climb of Mt. Rainier puts them to the test.