The film tells the tale of Nim Chimpsky, a chimpanzee who was the subject of a landmark experiment to see if an ape could learn to communicate with language if raised and nurtured like a human child. This study was the brainchild of Dr. Herbert Terrace, a Columbia University behavioral psychologist who hoped to teach Nim enough language that he could eventually express what he was thinking and feeling. This would refute Noam Chomsky's thesis that language is inherent only in humans, hence his moniker, a direct pun on the famous linguists' name. The doc was a smash when it played at Sundance with this entirely different incredible but true story

The inspirational story of Owen Suskind, a boy of considerable promise, until he developed autism at the age of 3. He was unable to speak until he and his family discovered a unique way to communicate by immersing themselves in the world of classic Disney animated films. This emotional coming-of-age story follows Owen as he graduates to adulthood and takes his first steps toward independence.

Dan Cohen, founder of the nonprofit organization Music & Memory, fights against a broken healthcare system to demonstrate music's ability to combat memory loss and restore a deep sense of self to those suffering from it.

Modern headlines are claiming mindfulness may cure anxiety, depression, and a whole host of other health problems. How can this simple practice of watching your own breath change the way your brain works? And can that change your life? The fourth episode of the series looks at the power of mindfulness and meditation. It examines different kinds on meditation (transcendental, dynamic, and religious) and notes that they are different from mindfulness meditation (Satipatthana). Also it talks to neuroscientists who discuss what happens in the brain during meditation.

This episodes the nature of the cosmos on the micro and atomic scales, using the Ship of the Imagination to explore these realms. Tyson describes some of the micro-organism that live within a dew drop, demonstrating parameciums and tardigrades. He proceeds to discuss how plants use photosynthesis via their chloroplasts to convert sunlight into chemical reactions that convert carbon dioxide and water into oxygen and energy-rich sugars. Tyson then discusses the nature of molecules and atoms and how they relate to the evolution of species. He uses the example set forth by Charles Darwin postulating the existence of the long-tongued Morgan's sphinx moth based on the nature of the comet orchid with pollen far within the flower. He further demonstrates that scents from flowers are used to trigger olfactory centers in the brain, stimulating the mind to threats as to aid in the survival of the species. Tyson narrates how Greek philosophers Thales and Democritus postulated that all matter was made up of combinations of atoms in a large number of configurations, and describes how carbon forms the basic building block for life on earth due to its unique chemical nature. Tyson explains on the basic atomic structure of protons, neutrons, and electrons, and the nature of nuclear fusion that occurs in most stars. He then discusses the existence of neutrinos that are created by these nuclear processes in stars, and that detecting such sub-atomic particles which normally pass through matter require subterranean facilities like the Super-Kamiokande that were used to detect neutrinos from the supernova SN 1987A in the Large Magellanic Cloud before light from the explosion were observed due to their ability to pass through matter of the dying sun. Tyson compares how neutrinos were postulated by Wolfgang Pauli to account for the conservation of energy from nuclear reactions in the same manner as Darwin's postulate on the long-tongued moth. Tyson concludes by noting that there are neutrinos from the Big Bang still existing in the universe but due to the nature of light, there is a "wall of infinity" that cannot be observed beyond.

Why do we sleep? And what does sleep have to do with memory, trauma, and our emotions? From fruit flies to whales, virtually every animal sleeps. But why? Why do we need to spend nearly a third of our lives in such a defenseless state? Scientists are peering more deeply into the sleeping brain than ever before, discovering just how powerful sleep can be, playing a role in everything from memory retention and emotional regulation to removing waste from our brains. So why are we getting so little of it?