A look into how the body defends itself against all odds through the stories of a nature survivalist, rancher twins, a doctor who survived Ebola and a cancer therapy recipient. The Immune System, essential to our survival every second, is the most complex and least understood piece of our biology.

In changing seas and oceans, cephalopods like the cuttlefish and the giant Pacific octopus must rely on their remarkable intelligence to survive. Their alien appearance comes with astonishing resources, independence, and invention. And there's still so much to learn about these rarely seen legends of the deep.

To recruit actors for his rehearsals, Nathan opens an acting studio in Los Angeles, teaching 'the Fielder Method', which involves covertly observing and imitating unaware subjects. Feeling insecure about his own performance, Nathan reenacts the class with actors and a fake Nathan as the teacher while the real Nathan plays the role of Thomas, a student. Nathan makes his students immerse themselves in other people's lives while he immerses himself in Thomas's life, even living in Thomas's home.
Nathan returns to Oregon, where his 'son', Adam, is now a teenager. Nathan and Joshua, the actor playing Adam, decide that Adam should lash out due to resentment of his absentee father and develop a drug problem, a situation that mirrors Angela's own past. Adam suffers an overdose and is tended to by emergency responders played by Thomas and another Fielder Method graduate. After he runs away from home, the 15-year-old Adam reverts to a 6-year-old since Nathan plans to relive his son's earlier years.

Rasputin is gone, but Nicholas II continues his catastrophic policies in war and at home. When Nicholas goes back to military headquarters, he is in fact leaving control of government, exactly when Russia needed to be held together by its Czar. The war by this time is deeply unpopular. It's not only unpopular, it's also arguably the engine that's causing enormous economic crisis, that's causing general unrest. Deprivation pushes the population from unrest to revolution.

Principles of generosity and prosperity inform the selection of the last two crew members: Christopher Sembroski, a former member of the U.S. Air Force who served in Iraq and now works as a Lockheed Martin engineer, and Sian Proctor, a professor of geosciences and two-time NASA astronaut candidate. Excitement for the flight ramps up, but anxiety lingers.

Sal takes uncharacteristically desperate measures in the face of new federal charges, an unearthed paper trail and increasing pressure on a confidant.