The film explores the revolutionary gene-editing tech now giving humankind the freedom to redraw the blueprint of biological life itself. We investigate not only the tremendous potential the technology holds, whether in the fight to eliminate diseases or in transforming agriculture to adapt to unprecedented climate extremes, but also probe the inherent risks involved and the potential for widespread abuse, dangers that could take our future down a very dark, dystopian path.

The journeys of the Voyager probes is put in the context of the Netherlands in the seventeenth century, with a centuries-long tradition of sailing ship explorers, and its contemporary thinkers (such as Constantijn Huygens and his son Christian). Their discoveries are compared to the Voyager probes' discoveries among the Jovian and Saturn systems. In Cosmos Update, image processing reconstructs Voyager’s worlds and Voyager’s last portrait of the Solar System as it leaves is shown.

The Sky at Night looks back at the last ten years of astronomy and ponders the most significant milestones and revelations. With the help of six distinguished astronomers, Chris and Maggie consider the state of astronomy in 2020 and wonder what new, exciting discoveries await us across the rest of the decade, as a host of new ground and space telescopes come online. Astronomer Royal Lord Martin Rees is among the guests to walk along the Astronomical Wall of Discovery in this one-hour special.

The episode, devoted to the planet Mars, begins with scientific and fictional speculation about the Red Planet during the late nineteenth and early twentieth centuries (H. G. Wells' The War of the Worlds, Edgar Rice Burroughs' science fiction books, and Percival Lowell's false vision of canals on Mars). It then moves to Robert Goddard's early experiments in rocket-building, inspired by reading science fiction, and the work by Mars probes, including the Viking, searching for life on Mars. The episode ends with the possibility of the terraforming and colonization of Mars and a Cosmos Update on the relevance of Mars' environment to Earth's and the possibility of a manned mission to Mars.

A look at the probes which explored our Solar System, laying the groundwork for a future spacecraft to search for life on a second Earth. That space craft must communicate, it must navigate, it must have power, it must have propulsion. We will have to give it all the intelligence necessary to make its own decisions. In 'The Explorers' the spacecraft Artemis initiates launch sequence and begins its 4.7 light year journey to Minerva B - an Earth-like exoplanet.

Brian Cox looks at our attempts to answer one of the most profound questions we can ask – are we alone in the universe? With scientists sending space probes to the furthest reaches of our solar system and beyond, the scientific search for alien life has begun. Inspired by a childhood love of science fiction, Brian still hopes to hear from ET. In this film, he explains why this search deserves to be taken seriously, and he explores the chances of it happening.