When Mahmud Pasha and his men were crossing the river at night, Vlad Dracula started his first attack on the Ottomans. However, Mehmed II was smart enough to know that Vlad would be waiting for them. Mehmed II counterattacks Vlad’s army, and we see the first great battle here.
After his victory, Mehmed's troops advance into Wallachia, and Vlad employs guerrilla tactics to weaken his rival. At one point, Vlad Dracula released some criminals with tuberculosis and bubonic plague in order to infect the Ottomans. He sent these infected criminals to the Ottoman camp at night, and it is considered a great tactic by the experts because we see Vlad Dracula practicing biological warfare. Meanwhile, a threat lurks in the imperial palace.

Vlad Dracula presses an increasingly desperate guerrilla campaign from the shadows, hoping to demoralize the Ottomans and slow their march north. After chasing Vlad for two weeks, sultan Mehmed II and his invading army find themselves caught in a nightmare come to life deep within the Wallachian forest. Many legends have arisen out of the invasion of Wallachia in 1462. One speaks of Vlad Dracula launching a biological attack against the Ottomans to slow their march to his capital city, Târgovişte. Vlad opened his prisons and released hardened criminals to go amongst the Ottomans with tuberculosis and bubonic plague so that they could infect the enemies.
Vlad Dracula also had carried out a scorched-earth policy against Mehmed II. Along with his hit-and-run campaign from the shadows has left the sultan's troops on edge. As Mehmed's army closes on Târgovişte, tensions flare in the Ottoman camp, where food and water are in increasingly short supply. But Vlad had nowhere to rely on food for himself either and there was nowhere to go anymore. He became a prisoner of his own scorched-earth policy. Radu Dracula closes in to take Princess Anastasia hostage. Anastasia commits suicide when he reach her at Poenari castle.