Magic mushrooms, long considered sacred by the Indigenous Mazatec in Mexico, become the subject of scientific studies measuring the intense effects of its Psilocybin and its potential therapeutic use.
In the second episode, we are introduced to Ben, who’s battled with crippling Obsessive-Compulsive Disorder (OCD) his entire life. When he had his firstborn, Ben’s life became full of panic attacks regarding his son’s safety, and he knew something had to change. Ben signed up for a psilocybin-assisted therapy clinical trial which was testing whether the psychedelic could help people with severe OCD. In the session under the influence of psilocybin, Ben felt decomposed and eventually grew into a tree. While living as a tree, he saw his human self, playing with his child. Though this sounds scary, from Ben’s perspective, it was beautiful. He was one with the universe, seeing himself in the ultimate third-person perspective. Finally, he saw how it could be different if he didn’t let his OCD control him. And several months out, all the symptoms disappeared.
Ben’s story is one of many told in this series, which gives hope that help is right around the corner for the millions who suffer —often in silence— with debilitating mental disorders. But Michael Pollan’s work is showcasing the success stories. Often, even in the most successful trials, psychedelic-assisted therapy only helps up to a third of people enter remission. More frequently, patients are helped —sometimes substantially— but they still suffer with their illnesses and some people aren’t helped at all.

The cosmos, with its billions of galaxies and countless stars, isn't the only one. We share our lives with another universe: The world of the small, of the viruses, of the bacteria. We call this strange hidden kingdom the Microcosmos. We share our world with the microcosmos. Will we coexist in an uneasy peace, or will it destroy us?
In 2020, A tiny virus caused a global pandemic, COVID-19. This pandemic makes people see the world completely differently, because there was an invisible universe, pretty much ignored for the most part. Very, very tiny things have a huge impact on our lives. The microcosmos is complex, while some parts kill us, others keep us alive. The microcosmos is responsible for the very oxygen that we breathe and the soil on which we live. And it will influence our future as we venture out into space.

Follow three women at risk of developing Alzheimer’s and join a groundbreaking study to try to prevent the disease, while sharing their ups and downs, anxiously watching for symptoms, and hoping they can make a difference. Barb, Sigrid, and Karen all had mothers with Alzheimer’s and witnessed first hand the devastation wrought by the disease, not only on the mind and body, but on patients’ families.

A look into how the body defends itself against all odds through the stories of a nature survivalist, rancher twins, a doctor who survived Ebola and a cancer therapy recipient. The Immune System, essential to our survival every second, is the most complex and least understood piece of our biology.

To maximize longevity, you might think it’s best to play it safe and stay cozy. But some scientists believe we should do the opposite, as exposure to extreme temperatures can trigger our bodies’ own defenses against the killer diseases of old age. Chris heads for the freezing Arctic with his brothers Liam and Luke to take on the ultimate cold therapy.

In the extraordinary final chapter, viewers are taken on a global journey to review regions renowned for their extreme longevity. From picturesque Sardinia to the serene landscapes of Okinawa and the vibrant community in Loma Linda, the film uncovers the secrets behind these remarkable Blue Zones. It offers a fascinating glimpse into the unique lifestyles and community dynamics that contribute to the residents' exceptional health and long lives, leaving viewers intrigued by the possibilities of enhancing their own well-being.
The film doesn't stop at showcasing these remarkable places; it also delves into innovative approaches to improve public health. By highlighting initiatives like Singapore's Proximity Housing Grant and the transformative Blue Zones project, the episode encourages viewers to reflect on the impact of environment and policy on individual health. Ultimately, it leaves audiences pondering how they can adapt these life-enhancing principles to enrich their own lives.