This episode covers the nature of how life may have developed on Earth and the possibility of life on other planets. Tyson begins by explaining how the human development of writing systems enabled the transfer of information through generations, describing how Princess Enheduanna ca. 2280 BCE would be one of the first to sign her name to her works, and how Gilgamesh collected stories, including that of Utnapishtim documenting a great flood comparable to the story of Noah's Ark. Tyson explains how DNA similarly records information to propagate life, and postulates theories of how DNA originated on Earth, including evolution from a shallow tide pool, or from the ejecta of meteor collisions from other planets. In the latter case, Tyson explains how comparing the composition of the Nakhla meteorite in 1911 to results collected by the Viking program demonstrated that material from Mars could transit to Earth, and the ability of some microbes to survive the harsh conditions of space. With the motions of solar systems through the galaxy over billions of years, life could conceivably propagate from planet to planet in the same manner. Tyson then moves on to consider if life on other planets could exist. He explains how Project Diana performed in the 1960s showed that radio waves are able to travel in space, and that all of humanity's broadcast signals continue to radiate into space from our planet. Tyson notes that projects have since looked for similar signals potentially emanating from other solar systems. Tyson then explains that the development and lifespan of extraterrestrial civilizations must be considered for such detection to be realized. He notes that civilizations can be wiped out by cosmic events like supernovae, natural disasters such as the Toba disaster, or even self-destruct through war or other means, making probability estimates difficult. Tyson describes how elliptical galaxies, in which some of the oldest red dwarf stars exist, would offer the best chance of finding established civilizations. Tyson concludes that human intelligence properly applied should allow our species to avoid such disasters and enable us to migrate beyond the Earth before the Sun's eventual transformation into a red giant.

The series, depicted by state of the art CGI techniques, and applying the laws of life on Earth to the rest of the galaxy, blends fact with science fiction and conceptualizes what alien life might be like on other planets.
In the prologue, astronomer Didier Queloz makes an appearance to discuss the discoveries of exoplanets and how they are analyzed in the real world. In Episode 1, the fictional world imagined is Atlas, a world with higher gravity than Earth and a thicker atmosphere leading to airborne creatures. In explaining the aliens of Atlas, the episode also explores the handicap principle in insects, and shows a rehabilitative form of falconry as captive falcons are trained to live in the wild.

The season 8 of Space Deepest Secrets shares the stories of deep-space explorers who are risking their careers, and even their lives, to lead humanity to worlds yet to be seen.
In the first episode, astronomers are laying the groundwork to locate a new planet for the human race to inhabit, and the more alien worlds they discover and encounter, the more they unmask the mysterious and truly destructive nature of the cosmos.

Embark on an astounding journey across 100,000 light-years to witness key moments in the history of the Milky Way. Using cutting-edge science, National Geographic constructs a 3-D state-of-the-art CGI model of our galaxy. We'll peer into the heart of the Milky Way on the hunt for super-massive black holes, watch how stars are born and die, fly out and above the plane of our galaxy to understand its true shape and scour its dusty spiral arms for the possibility of life

Humans have long gazed up at the night sky, wondering whether other lifeforms and intelligences could be thriving on worlds far beyond our own. But over the last few decades, ultra-sensitive telescopes and dogged detective work have transformed alien planet-hunting from science fiction into hard fact. We expected to find worlds similar to the planets in our own solar system, but we instead discovered a riot of exotic worlds. Vivid animation based on data from the most successful planet hunter of them all, the Kepler space telescope, brings these worlds into view: puffy planets with the density of polystyrene, unstable worlds orbiting two suns and 1,000-degree, broiling gas giants with skies whipped into titanic winds.
But perhaps the most startling discovery was the number of worlds that may be contenders for a second Earth, at the right distance from their sun to have that ingredient so crucial for life as we know it, liquid water. Amongst them, we witness the most tantalizing discovery of all: a so-called ‘super-Earth’, situated in the Goldilocks zone - the area just the right distance from a sun to potentially support life - and with the faint signal of water in its atmosphere.

In episode 3, Artemis arrives on the exoplanet Minerva B, but will she find evidence of life? This is a vision of our future, the fateful day in a far-flung corner of the universe, when a probe from Earth initiates the first descent onto an alien world, looking for proof of life beyond our solar system.
There are no witnesses, no cheering crowds in the control room. A decade or more will pass before news finally reaches us, back across the dark oceans of space. But the seeds of this mission are already being sowed today by the first generation of scientists bold enough to believe it could be possible.