Genetics

We humans often like to think we're the end of the line when it comes to evolution. But if we rewind through our short time on Earth as a species, and the many changes that have occurred to us along the way, we find we're still very much a work in progress. Renowned geneticist and author Spencer Wells reveals how changes in our genetic code have fuelled major changes in our appearance and capabilities over time, and why scientists believe we're continuing to rapidly evolve today. By understanding these changes, we are better prepared for the future.

The film explores the revolutionary gene-editing tech now giving humankind the freedom to redraw the blueprint of biological life itself. We investigate not only the tremendous potential the technology holds, whether in the fight to eliminate diseases or in transforming agriculture to adapt to unprecedented climate extremes, but also probe the inherent risks involved and the potential for widespread abuse, dangers that could take our future down a very dark, dystopian path.

'It's alive!' Since Dr. Frankenstein spoke those famous words, we've been alternately enthralled and terrified by the idea of creating life in the lab. Now, a revolution in genetic engineering and thrilling innovations in synthetic biology are bringing that dream—or nightmare, as the case may be—closer to reality. New tools allow researchers to use cells to create their own DNA and edit it into existing genomes with more ease and less cost than ever before.
Along with renewed hopes for treating some genetic diseases, there's serious talk of using the newest technologies to bring long-extinct animals back from the dead – like the team hoping to resurrect the woolly mammoth. Science fiction is quickly becoming science fact. Another daring genetic experiment to bioengineer animals could prevent Lyme disease. But the power to make life comes with deep ethical questions. What are the potential rewards—and dangers—of tinkering with nature? This films explores the benefits and the burden of risk surrounding the controversial new technology.

Dr Adam Rutherford shows how decoding the genome has led us to begin to understand the very process by which our DNA makes us different; how it makes each one of us on earth unique and influences who we are and the traits we have. He reveals how, as we try and understand the relationship between who we are and our genes, we stand at the beginning of the most exciting scientific journey of all time.

It is time to see if personalised dieting will work in normal life. The volunteers have been given one of three diets to follow - based on their genes, their hormones and their psychology. But now they are back at home, trying to stick to their personalised diets with all the stresses and temptations of real life. Dr Chris van Tulleken and Professor Tanya Byron discover how our genetic makeup can make temptation difficult to resist, how understanding the brain reveals what makes us comfort eat and what science can tell us about why we make disastrous food choices.