With the defeat of the Egyptian fleet at Actium, Mark Antony and Cleopatra retreat to their palace and await their fate. Believing that Cleopatra has taken her life, Mark Antony decides follow her into the afterlife. She has other plans however and is quite prepared to negotiate with Octavian if there is any possibility her life and those of her children will be spared. Cleopatra asks Vorenus to take her son Caesarian to safety and Octavian sends Pullo after them. The old friends are soon together again.

The big blue is the world's greatest wilderness, far from shore and many kilometres deep. It's a vast marine desert where there is little to eat and nowhere to hide. Yet it's home to some of the biggest and most spectacular creatures on earth. This episode reveals what it takes to survive in this savage and forbidding world. We witness feats of incredible endurance, moments of high drama and extraordinary acts of heart-wrenching self-sacrifice. Every animal in the big blue must find their own unique way to survive. Sperm whales have the largest brains in the world. They live for 80 years, and we are only now beginning to learn the extraordinary complexity of their language of clicks - thought to coordinate the whole family in everything from childcare to hunting. With special pressure-proof cameras, we witness record-breaking feats of endurance as they hunt for squid a kilometre down into the abyss. Only recently have we begun to solve the mystery of where baby turtles disappear to in their early years. They leave the crowded waters of the coast and head to the open ocean, where they use floating debris like logs as life rafts. Here they remain until adulthood, adrift on the high seas in relative safety away from coastal predators. Over half of all animals in the open ocean drift in currents. Jellyfish cross entire oceans feeding on whatever happens to tangle with their tentacles. The jelly-like Portuguese man-of-war can harness sail power to fish with its deadly tentacles. Sometimes there is a brief explosion of food in this marine desert, but ocean hunters must be fast to make the best of this bonanza. We witness super pods of up to 5,000 spinner dolphins racing to herd vast shoals of lanternfish, briefly caught at the surface where it is thought they spawn. New aerial footage reveals, for the first time, the truth to a centuries-old sailors' legend of the 'boiling seas' - the spectacular feeding frenzy of 90kg tuna and dolphins smashing through the lantern fish shoals turning the sea white with foam.

Mercedes' W13 Is put to the test at pre-season tests at Bahrain with Lewis Hamilton and new teammate George Russell behind the wheel. However, the car exhibits an incredibly unpleasant drive with an excessive amount of porpoising. The team has noticed the issue and plans to work on it before further tests commence. However, for Mercedes, the issue seems to remain unfixed. Indeed, the issues are present coming to the races at Imola, Spain, and Monaco, before arriving at the Baku City Circuit for Azerbaijan. Lewis' back starts to exhibit pain as he goes down the straights of Baku as Max Verstappen takes home the victory with Lewis taking fourth. After the race, the team principals convene for a meeting, where Toto Wolff of Mercedes expresses his dismay and concern about the safety of the drivers.
The Silverstone round, which also coincided with Zhou Guanyu's big crash coming into Abbey, finishes with Lewis Hamilton taking third place and Carlos Sainz Jr. taking his first career victory in Formula One. Lewis, having questioned the possibilities of retirement following the 2021 season, announces he is here to stay with Mercedes.

At an extraordinary moment in the history of one of the world’s oldest and most controversial drugs, Dr Javid Abdelmoneim investigates the very latest medical and scientific research into the effects of cannabis on the brain and the body, to find out whether it will help or harm patients.
Javid meets the young epilepsy patient responsible for changing the law around medicinal cannabis in the UK and sees the remarkable effects it has on his condition. He visits a medicinal cannabis farm in Denmark to learn how a company known for growing the recreational drug are now producing medicinal cannabis to be exported all over Europe. He travels to Israel, to find out why they have been using cannabis as a medicine for over 20 years and meets the scientists studying the safety and effectiveness of cannabis in treating pain. And he meets the so-called godfather of cannabis, who at 88 years old is still an active research scientist and considered the world’s leading cannabis expert.

As the landscape of work shifts, do we need a drastic rethinking of social safety nets? Do businesses need offices? Is a 9-to-5 workday valid? Does the nation need a drastic rethinking of the social safety nets? Does America face a 'post-work' era, or will there be increased inequities in how we make our livings?

Magic mushrooms, long considered sacred by the Indigenous Mazatec in Mexico, become the subject of scientific studies measuring the intense effects of its Psilocybin and its potential therapeutic use.
In the second episode, we are introduced to Ben, who’s battled with crippling Obsessive-Compulsive Disorder (OCD) his entire life. When he had his firstborn, Ben’s life became full of panic attacks regarding his son’s safety, and he knew something had to change. Ben signed up for a psilocybin-assisted therapy clinical trial which was testing whether the psychedelic could help people with severe OCD. In the session under the influence of psilocybin, Ben felt decomposed and eventually grew into a tree. While living as a tree, he saw his human self, playing with his child. Though this sounds scary, from Ben’s perspective, it was beautiful. He was one with the universe, seeing himself in the ultimate third-person perspective. Finally, he saw how it could be different if he didn’t let his OCD control him. And several months out, all the symptoms disappeared.
Ben’s story is one of many told in this series, which gives hope that help is right around the corner for the millions who suffer —often in silence— with debilitating mental disorders. But Michael Pollan’s work is showcasing the success stories. Often, even in the most successful trials, psychedelic-assisted therapy only helps up to a third of people enter remission. More frequently, patients are helped —sometimes substantially— but they still suffer with their illnesses and some people aren’t helped at all.