The second episode takes a look at how humans have always been voyagers and explorers, leaving the comfort of native shores to explore. Neil DeGrasse Tyson will show us a long-term vision of humanity's future worlds.

Richard Dawkins deals with some of the philosophical and social ramifications of the theory of evolution. Dawkins starts out in Kenya, speaking with palaeontologist Richard Leakey. He then visits Christ is the Answer Ministries, Kenya's largest Pentecostal church, to interview Bishop Bonifes Adoyo. Adoyo has led the movement to press Kenya's national museum to sideline its collection of hominid bones pointing to man's evolution from ape to human.[5] The collection includes the Turkana Boy discovered by Kamoya Kimeu, a member of a team led by Richard Leakey in 1984. Dawkins discusses social darwinism and eugenics, explaining how these are not versions of natural selection, and that 'Darwin has been wrongly tainted'. He then meets with evolutionary psychologist Steven Pinker to discuss how morals can be compatible with natural selection. He goes on to explaining sexual selection, with peafowls as an example. To find out whether sexual selection plays a role for altruism and kindness among humans, he visits women who are looking for sperm donors, as well as a sperm bank manager. Dawkins also explains kin selection and selfish genes.

Dr Alice Roberts re-traces the greatest ever journey taken by our ancestors. Thousands of years ago one small group of our species, Homo sapiens, crossed out of Africa and into the unknown. Their descendants faced baking deserts, sweat-soaked jungles and frozen wildernesses and risked everything on the vast empty ocean. Within 60,000 years they colonised the whole world... How did they do it? Why do we, their descendants all look so different?

Alice Roberts tries to find out how Stone Age people reached North and South America for the first time. She finds out about an ancient corridor through the Canadian ice sheet that might have allowed the first humans through. Old finds in Chile though point to a whole different route for the first humans making it there.

The journey continues into Asia, the world's greatest land mass, in a quest to discover how early hunter-gatherers managed to survive in one of the most inhospitable places on earth - the Arctic region of Northern Siberia. Alice also explores what may have occurred during human migration to produce Chinese physical characteristics, and considers a controversial claim about Chinese evolution: that the Chinese do not share the same African ancestry as other peoples.

Dr Alice Roberts looks at our ancestors' seemingly impossible journey to Australia. Miraculously preserved footprints and very old human fossils buried in the outback suggest a mystery: that humans reached Australia almost before anywhere else. How could they have travelled so far from Africa, crossing the open sea on the way, and do it thousands of years before they made it to Europe? The evidence trail is faint and difficult to pick up, but Alice takes on the challenge. In India, new discoveries among the debris of a super volcano hint that our species started the journey much earlier than previously thought, while in Malaysia, genetics points to an ancient trail still detectable in the DNA of tribes today. Alice travels deep into the Asian rainforests in search of the first cavemen of Borneo and tests out a Stone Age raft to see whether sea travel would have been possible thousands of years ago, before coming to a powerful conclusion.