The episode begins with Tyson describing how pattern recognition manifested in early civilization as using astronomy and astrology to predict the passing of the seasons, including how the passage of a comet was often taken as an omen. Tyson continues to explain that the origin of comets only became known in the 20th century due to the work of Jan Oort and his hypothesis of the Oort cloud. Tyson then continues to relate the collaboration between Edmond Halley and Isaac Newton in the last part of the 17th century in Cambridge. The collaboration would result in the publication of Philosophiæ Naturalis Principia Mathematica, the first major work to describe the laws of physics in mathematical terms, despite objections and claims of plagiarism from Robert Hooke and financial difficulties of the Royal Society of London. Tyson explains how this work challenged the prevailing notion that God had planned out the heavens, but would end up influencing many factors of modern life, including space flight. Tyson further describes Halley's contributions including determining Earth's distance to the sun, the motion of stars and predicting the orbit of then-unnamed Halley's Comet using Newton's laws. Tyson contrasts these scientific approaches to understanding the galaxy compared to what earlier civilizations had done, and considers this advancement as mankind's first steps into exploring the universe. The episode ends with an animation of the Milky Way and Andromeda galaxies' merging based on the principles of Newton's laws.

Imagine a world where infinite copies of you are playing out every storyline of your life. It sounds like a plot stolen straight from Hollywood, but far from it. This is the multiverse. Until very recently the whole idea of the multiverse was dismissed as a fantasy, but now this strangest of ideas is at the cutting edge of science. And for a growing number of scientists, the multiverse is the only way we will ever truly make sense of the world we are in. Do multiple universes exist? And if so, which one are we actually in?" Imagine a world where dinosaurs still walk the earth. A world where the Germans won World War II and you are president of the United States. Imagine a world where the laws of physics no longer apply.

Sagan reflects on the future of humanity and the question of 'who speaks for Earth?' when meeting extraterrestrials. He discusses the very different meetings of the Tlingit people and explorer Jean-François de La Perouse with the destruction of the Aztecs by Spanish conquistadors, the looming threat of nuclear warfare, and the threats shown by destruction of the Library of Alexandria and the murder of Hypatia. The episode ends with an overview of the beginning of the universe, the evolution of life, and the accomplishments of humanity and makes a plea to mankind to cherish life and continue its journey in the cosmos. The Cosmos Update notes the preliminary reconnaissance of planets with spacecraft, the fall of the Berlin Wall and the end of apartheid in South Africa, and measures towards the reduction of nuclear weapons.

Each night, across the planet, our cities illuminate the darkness. Their lights burning brighter than ever before. And whilst we're asleep, animals are making the most of this new neon landscape. The sunset in Los Angeles, Chicago, and Toronto creates worlds of opportunities for the cleverest animals willing to take the risk.

Imagine a tornado so powerful, it can form a planet, or winds sweeping across a planet but blowing at 6,000 miles per hour! How about rain....made of iron? Sounds like science fiction, but this type of weather is occurring daily in our solar system. Scientists are just beginning to unlock the secrets of these planets and their atmospheres. Can this research help scientists solve long unanswered questions that we have about Earth? As our own planet churns with the effects of global warming, it's natural to look into the heavens and wonder about the rest of the real estate.

Jeremy Clarkson decides to become a naturalist. 'In just 30 years, insect numbers have dropped by 25% and they're still falling. Without insects, all life on Earth ends. Everywhere where insects like to live is disappearing and I've decided to do something about that. My plan is to make my hedgerows, my valleys, my woods, and my streams more attractive to creepy crawlies. In essence, I am going to leave chunks of the farm completely alone. I'm going to put Mother Nature in the driving seat. It's a process called wilding.'