The episode begins with Tyson describing how pattern recognition manifested in early civilization as using astronomy and astrology to predict the passing of the seasons, including how the passage of a comet was often taken as an omen. Tyson continues to explain that the origin of comets only became known in the 20th century due to the work of Jan Oort and his hypothesis of the Oort cloud. Tyson then continues to relate the collaboration between Edmond Halley and Isaac Newton in the last part of the 17th century in Cambridge. The collaboration would result in the publication of Philosophiæ Naturalis Principia Mathematica, the first major work to describe the laws of physics in mathematical terms, despite objections and claims of plagiarism from Robert Hooke and financial difficulties of the Royal Society of London. Tyson explains how this work challenged the prevailing notion that God had planned out the heavens, but would end up influencing many factors of modern life, including space flight. Tyson further describes Halley's contributions including determining Earth's distance to the sun, the motion of stars and predicting the orbit of then-unnamed Halley's Comet using Newton's laws. Tyson contrasts these scientific approaches to understanding the galaxy compared to what earlier civilizations had done, and considers this advancement as mankind's first steps into exploring the universe. The episode ends with an animation of the Milky Way and Andromeda galaxies' merging based on the principles of Newton's laws.

NASA's revolutionary Juno Probe had a goal visiting Jupiter -- to reveal the deepest mysteries of the Solar System. Everything we see in the our planetary system today is affected by Jupiter somehow in the past or now. So in many ways, Juno is actually giving us a view into the history of the Solar System.
But there are many other questions. Does Jupiter have a core? Why it has a surprisingly warm atmosphere? What's driving Jupiter's storms? What is going on its weird cyclones, its gigantic swirls? The auroras of Jupiter are tremendously large, bigger than the planet itself. where are they coming from? What we're learning, what we're unlocking, it's mind-blowing.

Discover the Eras of the Universe and the answer to this big question: When Will Time End? Once the notion that the universe started with a rapid inflation nicknamed the Big Bang became accepted by the majority of scientists, many possible fates are predicted by rival scientific hypotheses, including futures of both finite and infinite duration. The ultimate fate of the universe is dependent on the shape of the universe and what role Dark energy will play as the universe ages.

We now know that the brain - the organ that more than any other makes us human - is one of the wonders of the universe, and yet until the 17th century it was barely studied. The twin sciences of brain anatomy and psychology have offered different visions of who we are. Now these sciences are coming together and in the process have revealed some surprising and uncomfortable truths about what really shapes our thoughts, feelings and desires. And the search to understand how our brains work has also revealed that we are all - whether we realise it or not - carrying out science from the moment we are born.

Black Holes are one of the most destructive forces in the universe, capable of tearing a planet apart and swallowing an entire star. Yet scientists now believe they could hold the key to answering the ultimate question - what was there before the Big Bang? The trouble is that researching them is next to impossible. Black holes are by definition invisible and there's no scientific theory able to explain them. Meet the astronomers attempting to image a black hole for the very first time and the theoretical physicists getting ever closer to unlocking their mysteries. It's a story that takes us into the heart of a black hole and to the very edge of what we think we know about the universe.

Sagan reflects on the future of humanity and the question of 'who speaks for Earth?' when meeting extraterrestrials. He discusses the very different meetings of the Tlingit people and explorer Jean-François de La Perouse with the destruction of the Aztecs by Spanish conquistadors, the looming threat of nuclear warfare, and the threats shown by destruction of the Library of Alexandria and the murder of Hypatia. The episode ends with an overview of the beginning of the universe, the evolution of life, and the accomplishments of humanity and makes a plea to mankind to cherish life and continue its journey in the cosmos. The Cosmos Update notes the preliminary reconnaissance of planets with spacecraft, the fall of the Berlin Wall and the end of apartheid in South Africa, and measures towards the reduction of nuclear weapons.