Scientists have no idea what it is, but Dark Matter and Dark Energy make up 96% of the Universe. Dark Matter is everywhere. It passes through everything we know on earth at billions of particles every second, yet no one has ever gotten a direct detection of this mysterious dark substance. An even more bewildering force is Dark Energy, which is rapidly pushing apart our Universe. Discovered only ten years ago, scientists are struggling to comprehend its unusual characteristics and answer the ultimate question; what is the fate of our Universe? Using cutting-edge computer graphics watch as the universe is brought down to earth.

This episodes the nature of the cosmos on the micro and atomic scales, using the Ship of the Imagination to explore these realms. Tyson describes some of the micro-organism that live within a dew drop, demonstrating parameciums and tardigrades. He proceeds to discuss how plants use photosynthesis via their chloroplasts to convert sunlight into chemical reactions that convert carbon dioxide and water into oxygen and energy-rich sugars. Tyson then discusses the nature of molecules and atoms and how they relate to the evolution of species. He uses the example set forth by Charles Darwin postulating the existence of the long-tongued Morgan's sphinx moth based on the nature of the comet orchid with pollen far within the flower. He further demonstrates that scents from flowers are used to trigger olfactory centers in the brain, stimulating the mind to threats as to aid in the survival of the species. Tyson narrates how Greek philosophers Thales and Democritus postulated that all matter was made up of combinations of atoms in a large number of configurations, and describes how carbon forms the basic building block for life on earth due to its unique chemical nature. Tyson explains on the basic atomic structure of protons, neutrons, and electrons, and the nature of nuclear fusion that occurs in most stars. He then discusses the existence of neutrinos that are created by these nuclear processes in stars, and that detecting such sub-atomic particles which normally pass through matter require subterranean facilities like the Super-Kamiokande that were used to detect neutrinos from the supernova SN 1987A in the Large Magellanic Cloud before light from the explosion were observed due to their ability to pass through matter of the dying sun. Tyson compares how neutrinos were postulated by Wolfgang Pauli to account for the conservation of energy from nuclear reactions in the same manner as Darwin's postulate on the long-tongued moth. Tyson concludes by noting that there are neutrinos from the Big Bang still existing in the universe but due to the nature of light, there is a "wall of infinity" that cannot be observed beyond.

Our universe seems real. But what if it’s a videogame? Scientists in a variety of fields are taking seriously the possibility that we live in a virtual reality. Maybe the Big Bang was just the moment someone flipped the switch and turned on our universe. Maybe what looks random has already been programmed to happen. If some advanced civilization did design and program our universe, would we ever know? Scientists are looking for glitches in the laws of the universe that may uncover its hidden code.

Particle physicist Prof. Brian Cox asks, 'What time is it?' It's a simple question and it sounds like it has a simple answer. But do we really know what it is that we're asking? Brian visits the ancient Mayan pyramids in Mexico where the Maya built temples to time. He finds out that a day is never 24 hours and meets Earth's very own Director of Time. He journeys to the beginning of time, and goes beyond within the realms of string theory, and explores the very limit of time. He discovers that we not only travel through time at the speed of light, but the experience we feel as the passing of time could be an illusion.

Time is woven into the fabric of the universe as one of the dimensions in which we live our daily lives. But maybe it is only a brain state that we use to piece together events. Could it exist only in our minds? Your sense of time can be totally different than the person next to you. This and other theories illustrate that time is an illusion and does not really exist. The world's top physicists tackle this fundamental question, does time exist, and offer new ways to perceive the physical world.

Does the universe, have a limit? Does the universe have an edge? Looking out to the edge of the universe is tremendously important to understand our place in the cosmos and to understand the universe itself.
Inflation was a formative moment for our universe. By the time it stopped, the universe's basic characteristics were set. There could be regions of the greater universe where inflation didn't stop then. Occasionally a little region will stop inflating and just expand at the normal rate. We could imagine a super large-scale structure where there's different regions of the universe, domains, and each domain has different local constants and laws of physics.