Our lifespan is increasing by 2.5 years every decade - and a third of all babies born today can expect to live to 100. But living longer can come at a cost. Old age itself brings with it a range of debilitating illnesses, many of which are the result of accumulating damage during our lifetime. Three diseases in particular have become the main killers in the developed world - cancer, heart disease and dementia. But a revolution in bio-medicine is now offering new hope for the treatment of these ailments, and the potential to extend our lives still further. Methods such as gene editing and stem cell therapies are transforming the way medicine can conquer disease today. "How to Live Longer" counts with the guide of the Nobel laureate Sir Paul Nurse, for whom the big question isn't just what science can do to fix our bodies and extend our lives, but whether it's right to use all the tools and techniques available.

Has the age of antibiotics come to an end? From a young girl thrust onto life support in Arizona to an uncontrollable outbreak at one of the nation’s most prestigious hospitals, The film investigates the alarming rise of a deadly type of bacteria that our modern antibiotics can’t stop.

Reporter Dr. Graham Phillips examines the effects of meditation in his own life, and the medical evidence of how it affects those who practice it. Can meditation literally make your brain younger?

Modern headlines are claiming mindfulness may cure anxiety, depression, and a whole host of other health problems. How can this simple practice of watching your own breath change the way your brain works? And can that change your life? The fourth episode of the series looks at the power of mindfulness and meditation. It examines different kinds on meditation (transcendental, dynamic, and religious) and notes that they are different from mindfulness meditation (Satipatthana). Also it talks to neuroscientists who discuss what happens in the brain during meditation.

Over a person's lifetime they are likely to be prescribed more than 14,000 pills. Antibiotics, cholesterol lowering tablets, anti-depressants, painkillers, even tablets to extend youth and improve performance in bed. These drugs perform minor miracles day after day, but how much is really known about them? Drug discovery often owes as much to serendipity as to science, and that means much is learnt about how medicines work, or even what they do, when they're taken. By investigating some of the most popular pills people pop, Horizon asks, how much can they be trusted to do what they are supposed to?

The final episode of this series looks at what happens to the brain when someone uses psychedelic drugs. It looks at how psychedelic drugs may be useful in dealing with anxiety in cancer survivors and serious depression. It explores the history of psychedelics and examines early medical experimentation with the drug. It also discussed why psychedelics were banned and examines how they affect the brain.