In the third episode of the series, Morgan Freeman examines different faiths' concepts of God, discovering how monotheism began in Egypt and Israel and allowing a neuroscientist to examine his own brain.

‘Who Is in Control?’ explores the great deception that greets us each morning when we awake: it feels as though we are in conscious control of our lives but the truth is that we are not. Instead almost every action, every decision, every belief that we hold is driven by parts of the brain that we have no access to.

Sagan reflects on the future of humanity and the question of 'who speaks for Earth?' when meeting extraterrestrials. He discusses the very different meetings of the Tlingit people and explorer Jean-François de La Perouse with the destruction of the Aztecs by Spanish conquistadors, the looming threat of nuclear warfare, and the threats shown by destruction of the Library of Alexandria and the murder of Hypatia. The episode ends with an overview of the beginning of the universe, the evolution of life, and the accomplishments of humanity and makes a plea to mankind to cherish life and continue its journey in the cosmos. The Cosmos Update notes the preliminary reconnaissance of planets with spacecraft, the fall of the Berlin Wall and the end of apartheid in South Africa, and measures towards the reduction of nuclear weapons.

Bitcoin is the world's leading virtual currency, but unlike real money, it is not backed by a government or properly regulated. Bitcoin is exchanged and held digitally by users - which is attractive to criminals selling drugs, pornography and arms. But now Bitcoin is moving into the mainstream and being openly marketed as an investment opportunity. The film investigates what Bitcoin is and what it means, going inside a Bitcoin mine in Iceland - where currency is made - and spending time with the Bitcoin millionaires of Silicon Valley.
The programme also hears from others who have been scammed out of their life savings and investors who think the cryptocurrency is an enormous scam and that the writing is on the wall. Around the world, authorities are sounding the alarm that Bitcoin is too risky - is it too late, or too crazy, to try to become a Bitcoin millionaire?

In ‘Who will we be?’ Dr. David Eagleman journeys into the future, and asks what’s next for the human brain, and for our species. We stand at a major turning point, one where we might take control of our own development. We face a future of uncharted possibilities in which our relationship with our own body, our relationship with the world, the very basic nature of who we are is set to be transformed. For thousands of generations, humans have lived the same life cycle over and over. We are born, we control a fragile body, we experience a limited reality, and we die. But science and technology are giving us tools to transcend that evolutionary story. Our brains don't have to remain as we have inherited them. We are capable of extending our reality, of inhabiting new bodies, and possibly shedding our physical forms altogether. And we are discovering the tools to shape our own destiny. Who we become is up to us.

The world is affected by an obesity epidemic, but why is it that not everyone is succumbing? Medical science has been obsessed with this subject and is coming up with some unexpected answers. As it turns out, it is not all about exercise and diet. At the centre of this programme is a controversial overeating experiment that aims to identify exactly what it is about some people that makes it hard for them to bulk up.