The episode, devoted to the planet Mars, begins with scientific and fictional speculation about the Red Planet during the late nineteenth and early twentieth centuries (H. G. Wells' The War of the Worlds, Edgar Rice Burroughs' science fiction books, and Percival Lowell's false vision of canals on Mars). It then moves to Robert Goddard's early experiments in rocket-building, inspired by reading science fiction, and the work by Mars probes, including the Viking, searching for life on Mars. The episode ends with the possibility of the terraforming and colonization of Mars and a Cosmos Update on the relevance of Mars' environment to Earth's and the possibility of a manned mission to Mars.

We think of comets as beautiful glowing balls of light streaking across our skies with their long sweeping tails, yet comets are so much more than just a cosmic firework display. Comets have a uniquely important place in modern science. As time machines from the early universe, they could hold the key to unlock the secrets of the cosmos. Comets could even be the origin of life itself. We follow the incredible odyssey of a comet as it sails through the solar system, watching it's every move as it evolves from a dormant chunk of ice and rock into a tumbling, violently active nucleus engulfed in a gaseous haze. What we learn is a revelation; comets are even more mysterious and fascinating than we had ever imagined.

At 11 o'clock on New Year's Eve of the Cosmic Calendar, Homo erectus stood up for the first time, freeing its hands and earning the species its name. They began to move around, to explore, daring to risk everything to get to unknown places. Our Neanderthal relatives lived much as we did and did many of the things we consider to be 'human.' More restless than their cousins the Neanderthals and Denisovans, our Homo sapiens ancestors crossed seas and unforgiving landscapes, changing the land, ocean and atmosphere, leading to mass extinction. The scientific community gave our age a new name, 'Anthropocene.'
Since the first civilizations we've wondered if there's something about human nature that contains the seeds of our destruction. Syukuro Manabe was born in rural Japan and took an intense interest in Earth's average global temperature. In the 1960's, he would assemble the evidence he needed to predict the increase of Earth's temperature due to greenhouse gases until it becomes an uninhabitable and toxic environment, leading to our extinction. 'This doesn't have to be,' says Neil deGrasse Tyson, 'it's not too late. There's another hallway, another future we can still have; we'll find a way.'

The Universe as we know it is condemned to death. Space, matter and even time will one day cease to exist and there's nothing we can do about it. Harsh realities are revealed about the future of our Universe; it may collapse and burn or it might be gripped by a galactic ice age. Either of these scenarios might be a long way off. However, our Universe could suddenly be destroyed by a "random quantum fluctuation", a bubble of destruction that can obliterate the entire cosmos in the blink of an eye. No matter how it ends, life in our Universe is doomed.

Today, we know black holes exist, and now scientists are trying to confirm that other holes lurk in hyperspace. Our infinite cosmos could contain a variety of "holes" such as black, white, "mini" and wormholes. White holes are the reverse of black holes; instead of matter being sucked into it, matter is ejected out. Wormholes are gateways in the fabric of space and time. They are included in Einstein's field equations as possibilities for their existence. Neither white holes nor wormholes have ever been found. Learn about new discoveries including, colliding binary black holes, intermediate black holes and manufacturing mini black holes.

Carl Sagan opens the program with a description of the cosmos and the Spaceship of the Imagination. The ship journeys through the universe's hundred billion galaxies, the Local Group, the Andromeda Galaxy, the Milky Way, the Orion Nebula, our Solar System, and finally the planet Earth. Eratosthenes' successful calculation of the circumference of Earth leads to a description of the ancient Library of Alexandria. Finally, the Ages of Science are described, before pulling back to the full span of the Cosmic Calendar.