Hosted by Morgan Freeman, this series explores the deepest mysteries of existence. These questions have been pondered by the most exquisite minds of the human race. Now, science has evolved to the point where hard facts and evidence may be able to provide us with answers instead of philosophical theories. In the first episode of the season 7, terrorists, like any group, have a cause to rally around. But for them, the cause justifies the deliberate targeting of innocent civilians. How can they think that way? Now, science is peering into the dark heart of terror networks to find out why.

The episode begins with Tyson describing how pattern recognition manifested in early civilization as using astronomy and astrology to predict the passing of the seasons, including how the passage of a comet was often taken as an omen. Tyson continues to explain that the origin of comets only became known in the 20th century due to the work of Jan Oort and his hypothesis of the Oort cloud. Tyson then continues to relate the collaboration between Edmond Halley and Isaac Newton in the last part of the 17th century in Cambridge. The collaboration would result in the publication of Philosophiæ Naturalis Principia Mathematica, the first major work to describe the laws of physics in mathematical terms, despite objections and claims of plagiarism from Robert Hooke and financial difficulties of the Royal Society of London. Tyson explains how this work challenged the prevailing notion that God had planned out the heavens, but would end up influencing many factors of modern life, including space flight. Tyson further describes Halley's contributions including determining Earth's distance to the sun, the motion of stars and predicting the orbit of then-unnamed Halley's Comet using Newton's laws. Tyson contrasts these scientific approaches to understanding the galaxy compared to what earlier civilizations had done, and considers this advancement as mankind's first steps into exploring the universe. The episode ends with an animation of the Milky Way and Andromeda galaxies' merging based on the principles of Newton's laws.

To show what the USA can learn from rest of the world, director Michael Moore playfully visits various nations in Europe and Africa as a one-man "invader" to take their ideas and practices for America. Whether it is Italy with its generous vacation time allotments, France with its gourmet school lunches, German with its industrial policy, Norway and its prison system, Tunisia and its strongly progressive women's policy and Iceland and its strong female presence in government and business among others, Michael Moore discovers there is much that American should emulate

In the third episode of the series, Morgan Freeman examines different faiths' concepts of God, discovering how monotheism began in Egypt and Israel and allowing a neuroscientist to examine his own brain.

Sagan reflects on the future of humanity and the question of 'who speaks for Earth?' when meeting extraterrestrials. He discusses the very different meetings of the Tlingit people and explorer Jean-François de La Perouse with the destruction of the Aztecs by Spanish conquistadors, the looming threat of nuclear warfare, and the threats shown by destruction of the Library of Alexandria and the murder of Hypatia. The episode ends with an overview of the beginning of the universe, the evolution of life, and the accomplishments of humanity and makes a plea to mankind to cherish life and continue its journey in the cosmos. The Cosmos Update notes the preliminary reconnaissance of planets with spacecraft, the fall of the Berlin Wall and the end of apartheid in South Africa, and measures towards the reduction of nuclear weapons.

Bitcoin is the world's leading virtual currency, but unlike real money, it is not backed by a government or properly regulated. Bitcoin is exchanged and held digitally by users - which is attractive to criminals selling drugs, pornography and arms. But now Bitcoin is moving into the mainstream and being openly marketed as an investment opportunity. The film investigates what Bitcoin is and what it means, going inside a Bitcoin mine in Iceland - where currency is made - and spending time with the Bitcoin millionaires of Silicon Valley.
The programme also hears from others who have been scammed out of their life savings and investors who think the cryptocurrency is an enormous scam and that the writing is on the wall. Around the world, authorities are sounding the alarm that Bitcoin is too risky - is it too late, or too crazy, to try to become a Bitcoin millionaire?