According to recent science the Neanderthals are not the knuckle-dragging apemen of popular imagination. The first part of the film investigates what Neanderthals looked like and how they lived in their Ice Age world. They were faster, smarter, better looking - and much more like us than we ever thought. Our guide is Ella Al-Shamahi, who enlists the skills of Andy Serkis, the master of performance capture, and a group of experts to investigate deeply Neanderthals appearance.
In the second part, Ella explores the fate of the Neanderthals - asking why they became extinct, and discovering how they live on inside of us today. About 2% of the DNA of most people is of Neanderthal origin - and it continues to affect us today. Neanderthals were a people who were supremely well adapted to their environment. But about 40,000 years ago they disappeared. Why?

The film explores the revolutionary gene-editing tech now giving humankind the freedom to redraw the blueprint of biological life itself. We investigate not only the tremendous potential the technology holds, whether in the fight to eliminate diseases or in transforming agriculture to adapt to unprecedented climate extremes, but also probe the inherent risks involved and the potential for widespread abuse, dangers that could take our future down a very dark, dystopian path.

To survive Mars, our species will need to evolve how we eat, drink, and build our homes. Will we need our genes to evolve as well? Sometime in the future humans will leave Earth to colonize Mars, and in doing so will begin to adapt to life on another planet in surprising ways. Evolutionary biologist Dr. Scott Solomon foresees a series of changes to our species from the size of our hearts and heads to the pigments in our skin.

A look into how the body defends itself against all odds through the stories of a nature survivalist, rancher twins, a doctor who survived Ebola and a cancer therapy recipient. The Immune System, essential to our survival every second, is the most complex and least understood piece of our biology.

Some 30 million Americans have sent their DNA to be analysed by companies like 23andMe and AncestryDNA. But what happens once the sample is in the hands of testing companies, and how accurate are their results? The film explores the power of genetic data to reveal family connections, ancestry, and health risks—and even solve criminal cold cases.

Without the chemistry of photosynthesis, ozone, and a molecule called Rubisco, none of us would be here. So how did we get so lucky? To find out, host David Pogue investigates the surprising molecules that allowed life on Earth to begin, and ultimately thrive. Along the way, he finds out what we’re all made of—literally.