Our lifespan is increasing by 2.5 years every decade - and a third of all babies born today can expect to live to 100. But living longer can come at a cost. Old age itself brings with it a range of debilitating illnesses, many of which are the result of accumulating damage during our lifetime. Three diseases in particular have become the main killers in the developed world - cancer, heart disease and dementia. But a revolution in bio-medicine is now offering new hope for the treatment of these ailments, and the potential to extend our lives still further. Methods such as gene editing and stem cell therapies are transforming the way medicine can conquer disease today. "How to Live Longer" counts with the guide of the Nobel laureate Sir Paul Nurse, for whom the big question isn't just what science can do to fix our bodies and extend our lives, but whether it's right to use all the tools and techniques available.

The film explores the revolutionary gene-editing tech now giving humankind the freedom to redraw the blueprint of biological life itself. We investigate not only the tremendous potential the technology holds, whether in the fight to eliminate diseases or in transforming agriculture to adapt to unprecedented climate extremes, but also probe the inherent risks involved and the potential for widespread abuse, dangers that could take our future down a very dark, dystopian path.

Could the source of the world’s deadliest viruses hold the secret to a healthier and longer life? Bats have a sinister reputation as potential sources for some of the deadliest disease outbreaks: Ebola, MERS, SARS, and most recently, the virus behind the COVID-19 global pandemic. Yet scientists are discovering new evidence that bats are biological marvels and may hold a key to longevity. They’re resistant to the diseases they carry and have freakishly long lifespans for their tiny size.
So, what’s their secret? And what else can we learn from their peculiar biology? From caves in Thailand and Texas to labs around the globe, the films meets the scientists who are decoding the superpowers of the bat.

To maximize longevity, you might think it’s best to play it safe and stay cozy. But some scientists believe we should do the opposite, as exposure to extreme temperatures can trigger our bodies’ own defenses against the killer diseases of old age. Chris heads for the freezing Arctic with his brothers Liam and Luke to take on the ultimate cold therapy.