There is a region of space that is dangerous for reasons we don't yet understand completely. We see an increased flux of energetic particles in this area and higher-than-usual levels of radiation. It's called the South Atlantic Anomaly. Some scientists now think the long-term effects of this danger zone may be far wider reaching than anyone ever expected, and it may even have implications for the future of humanity in space and on Earth.

On July 4, 2012, scientists at the giant atom smashing facility at CERN announced the discovery of a subatomic particle that seems like a tantalizingly close match to the elusive Higgs Boson, thought to be responsible for giving all the stuff in the universe its mass. Since it was first proposed nearly fifty years ago, the Higgs has been the holy grail of particle physicists: finding it completes the 'standard model" that underlies all of modern particle physics. Now CERN's scientists are preparing for the Large Hadron Collider's second act, when they restart the history-making collider, running at higher energy--hoping to find the next great discovery that will change what we know about the particles and forces that make up our universe.

Cosmic rays capable of destroying human DNA are hurtling through outer space like subatomic bullets, causing space crews radiation damage.
Cosmic rays are intergalactic alien interlopers on our Milky Way. But the source of their power is a mystery. Are they coming from other galaxies? Are they coming from things in between the galaxies? Where do cosmic rays come from? Truth is, the most powerful ones, we haven't got a clue. The race is on to solve the mystery of the fastest particles in the universe.

Scientists have no idea what it is, but Dark Matter and Dark Energy make up 96% of the Universe. Dark Matter is everywhere. It passes through everything we know on earth at billions of particles every second, yet no one has ever gotten a direct detection of this mysterious dark substance. An even more bewildering force is Dark Energy, which is rapidly pushing apart our Universe. Discovered only ten years ago, scientists are struggling to comprehend its unusual characteristics and answer the ultimate question; what is the fate of our Universe? Using cutting-edge computer graphics watch as the universe is brought down to earth.

While scientists have previously theorised about a “Big Crunch” where the universe retracts back to its original size, the discovery of Dark Matter and Dark Energy has placed that hypothesis on the backburner. Some astronomers now believe that if Dark Matter offsets Dark Energy then as the universe slowly expands, stars will gradually fade, running out of fuel and leading to a dark, cold and lifeless universe. Others hypothesise a much more violent end where Dark Energy continues to expand the universe at a greater and greater speed. Stronger than gravity, Dark Energy would pull apart everything down to the fundamental particles – the universe’s very fibres. While the universe’s end may be 50 billion years away, great leaps in science will continue to alter how we believe the universe was formed – and how it will end.

This episodes the nature of the cosmos on the micro and atomic scales, using the Ship of the Imagination to explore these realms. Tyson describes some of the micro-organism that live within a dew drop, demonstrating parameciums and tardigrades. He proceeds to discuss how plants use photosynthesis via their chloroplasts to convert sunlight into chemical reactions that convert carbon dioxide and water into oxygen and energy-rich sugars. Tyson then discusses the nature of molecules and atoms and how they relate to the evolution of species. He uses the example set forth by Charles Darwin postulating the existence of the long-tongued Morgan's sphinx moth based on the nature of the comet orchid with pollen far within the flower. He further demonstrates that scents from flowers are used to trigger olfactory centers in the brain, stimulating the mind to threats as to aid in the survival of the species. Tyson narrates how Greek philosophers Thales and Democritus postulated that all matter was made up of combinations of atoms in a large number of configurations, and describes how carbon forms the basic building block for life on earth due to its unique chemical nature. Tyson explains on the basic atomic structure of protons, neutrons, and electrons, and the nature of nuclear fusion that occurs in most stars. He then discusses the existence of neutrinos that are created by these nuclear processes in stars, and that detecting such sub-atomic particles which normally pass through matter require subterranean facilities like the Super-Kamiokande that were used to detect neutrinos from the supernova SN 1987A in the Large Magellanic Cloud before light from the explosion were observed due to their ability to pass through matter of the dying sun. Tyson compares how neutrinos were postulated by Wolfgang Pauli to account for the conservation of energy from nuclear reactions in the same manner as Darwin's postulate on the long-tongued moth. Tyson concludes by noting that there are neutrinos from the Big Bang still existing in the universe but due to the nature of light, there is a "wall of infinity" that cannot be observed beyond.